Anaphylaxis, the most dangerous form of allergy, can result in fatality within minutes of exposure to an allergen. Data from high-income countries show that hospital admissions for anaphylaxis increased during the past 20 years, although numbers of fatalities did not increase. A report in Clinical and Experimental Allergy describes the first comprehensive evaluation of trends in anaphylaxis admissions and fatal anaphylaxis in a low or middle income country—in this case, Brazil.
Investigators found increasing rates of hospital admissions for anaphylaxis between 2011 and 2019 in Brazil, a middle-income country, side effects metformin and alcohol which is similar to findings from high-income countries; however, they also found increasing fatal anaphylaxis rates.
Fatality rates were higher in Brazil than in most other national studies—more than 5% of people admitted to a hospital for anaphylaxis died, compared with approximately 1% in studies from high-income settings.
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